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Monascuspiloin
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Monascuspiloin

HY-N12124 · 500 g

MedChemExpress · Cat: HY-N12124

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Catalog No: HY-N12124
CAS No: 1011244-19-1
Category: Apoptosis
Pack Size: 500 g
Brand: MedChemExpress

Description

Monascuspiloin Monascinol exhibits anti-androgenic activity with an IC50 of 7 ?M. Monascuspiloin inhibits viability of PC-3 and LNCaP with IC50 of 45 and 47 ?M. Monascuspiloin induces apoptosis in LNCaP through inhibition of Akt/mTOR signaling pathway, induces autophagy through activation AMPK signaling pathway and arrest cell cycle at G2/M phase in PC-3. Monascuspiloin exhibits antitumor efficacy in mice.

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