Mono-Methyl-Histone H3 (Lys4) Rabbit Polyclonal Antibody

Description

EnkiLife offers the Mono-Methyl-Histone H3 (Lys4) Rabbit Polyclonal Antibody. This antibody reacts with Human,Mouse,Rat species and is suitable for WB,IHC,ICC/IF application. Alternative Names of Immunogen: H3K4me; H3 histone; HIST1H3A; Histone cluster 1; H3a. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200 Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. Research Area: Epigenetics and Nuclear Signaling