Mouse TUG Mouse Monoclonal Antibody

Description

EnkiLife offers the Mouse TUG Mouse Monoclonal Antibody. This antibody reacts with Mouse species and is suitable for WB,ELISA application. Alternative Names of Immunogen: ASPCR1, ASPL, ASPS, RCC17, TUG, UBXD9, UBXN9. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,ELISA 1:5000-1:20000 Background: The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.