

HY-147691 · 50 mg
MedChemExpress · Cat: HY-147691
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medchemexpress.com/mpo-in-5.htmlDescription
MPO-IN-5 compound 1 is a potent, irreversible MPO myeloperoxidase inhibitor. MPO-IN-5 inhibits MPO peroxidation and hERG binding, with IC50 values of 0.22 and 2.8 ?M, respectively. MPO-IN-5 shows rapid kinetics of inhibition, with enzyme inactivation rate kinact/Ki of 23000 M?1s?1.