GENERAL CATALOGUE
MRGPRX1 agonist 1
HY-130118 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-130118
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medchemexpress.com/mrgprx1-agonist-1.htmlCatalog No: HY-130118
CAS No: 2377379-39-8
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
MRGPRX1 agonist 1 is a highly potent MRGPRX1 agonist EC50=50 nM with greater than 50-fold selectivity for ?, ?, and ? opioid receptors. MRGPRX1 agonist 1 is inactive against MRGPRC11. MRGPRC11 inhibits high voltage-activated HVA Ca2+ currents, reduces neurotransmitter release, and mitigates nociceptive transmission in the spinal cord. MRGPRX1 agonist 1 is useful for the study of chronic pain, especially neuropathic pain.
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