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MRGPRX1 agonist 4
GENERAL CATALOGUE

MRGPRX1 agonist 4

HY-143880 · 50 mg

MedChemExpress · Cat: HY-143880

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Catalog No: HY-143880
CAS No: 2764889-60-1
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress

Description

MRGPRX1 agonist 4 compound 1t is a potent and orally active Mas-related G protein-coupled receptor X1 MRGPRX1 positive allosteric modulator with an EC50 value of 0.1 ?M. MRGPRX1 agonist 4 has good metabolic stability and oral bioavailability. MRGPRX1 agonist 4 can reduce behavioral heat hypersensitivity in a neuropathic pain model humanized MRGPRX1 mice. MRGPRX1 agonist 4 can be used for researching neuropathic pain.

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