

HY-143880 · 50 mg
MedChemExpress · Cat: HY-143880
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medchemexpress.com/mrgprx1-agonist-4.htmlDescription
MRGPRX1 agonist 4 compound 1t is a potent and orally active Mas-related G protein-coupled receptor X1 MRGPRX1 positive allosteric modulator with an EC50 value of 0.1 ?M. MRGPRX1 agonist 4 has good metabolic stability and oral bioavailability. MRGPRX1 agonist 4 can reduce behavioral heat hypersensitivity in a neuropathic pain model humanized MRGPRX1 mice. MRGPRX1 agonist 4 can be used for researching neuropathic pain.







