GENERAL CATALOGUE
Mrgx2 antagonist-3
HY-176446 · 50 mg
MedChemExpress · Cat: HY-176446
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medchemexpress.com/mrgx2-antagonist-3.htmlCatalog No: HY-176446
CAS No: 2641397-91-1
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
Mrgx2 antagonist-3 Compound B-40 is a highly selective antagonist of MrgX2 receptor with an IC50 value of 0.042-2.5 nM. Mrgx2 antagonist-3 blocks downstream G protein signaling and ?-Arrestin recruitment, thereby inhibiting MrgX2 receptor-mediated calcium influx and cellular degranulation. Mrgx2 antagonist-3 is promising for research of inflammation-related diseases and pruritus, such as chronic urticaria, allergic asthma.
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