GENERAL CATALOGUE
MRK-740
HY-114209 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-114209
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Manufacturer product page
medchemexpress.com/mrk-740.htmlCatalog No: HY-114209
CAS No: 2387510-80-5
Category: Epigenetics
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
MRK-740, a chemical probe, is a potent, selective and substrate-competitive PRDM9 histone methyltransferase inhibitor with an IC50 of 80?nM. MRK-740 is more selective for PRDM9 than other histone methyltransferases and other non-epigenetic targets. MRK-740 reduces PRDM9-dependent trimethylation of H3K4 IC50?=?0.8??M .
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