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MRT68921 dihydrochloride
GENERAL CATALOGUE

MRT68921 dihydrochloride

HY-100006A · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-100006A

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Catalog No: HY-100006A
CAS No: 2080306-21-2
Category: Autophagy
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

MRT68921 dihydrochloride is a potent NUAK1/ULK1 dual inhibitor. MRT68921 dihydrochloride inhibits ULK1 and ULK2 with IC50 values of 2.9 nM and 1.1 nM, respectively. MRT68921 dihydrochloride can block cells autophagy and kill tumor cells by breaking the balance of oxidative stress signals. MRT68921 dihydrochloride can inhibit cell proliferation and induce ROS production and apoptosis. MRT68921 dihydrochloride can be used for the research of cancer, such as breast cancer.

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