GENERAL CATALOGUE
MRTX-EX185
HY-145962 · 50 mg
MedChemExpress · Cat: HY-145962
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/mrtx-ex185.htmlCatalog No: HY-145962
CAS No: 2621927-57-7
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
MRTX-EX185 is a potent KRAS G12D inhibitor with an IC50 of 90 nM. MRTX-EX185 can binds both GDP-loaded and active GNP states of KRAS and KRAS G12D . MRTX-EX185 exhibits broad-spectrum binding properties with IC50s of 110, 290, 130 and 240 nM for KRAS WT, KRAS G12C , KRAS Q61H , KRAS G13D . MRTX-EX185 also binds GDP-loaded HRAS. MRTX-EX185 can be used to study various RAS-driven tumors such as pancreatic cancer .
More from MedChemExpress
GPR120 Agonist 1
HY-108711
GPCR G Protein
AG-045572
HY-107534
GPCR G Protein
Pamabrom
HY-17391
GPCR G Protein
ZD-7114
HY-101320
GPCR G Protein
Vasopressin Dimer (anti-parallel) (TFA)
HY-P5214
GPCR G Protein
Zimeldine-d6
HY-118835S
GPCR G Protein
ZM241385 (Standard)
HY-19532R
GPCR G Protein
(5S,6S)-DiHETE
HY-130138
GPCR G Protein