GENERAL CATALOGUE
MS105
HY-171830 · 1 mg
MedChemExpress · Cat: HY-171830
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Catalog No: HY-171830
CAS No: 2408339-39-7
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
MS105 YX39-105 is an orally active and selective protein tyrosine kinase 6 PTK6 PROTAC degrader. MS105 recruits VHL E3 ligase via the VHL ligand moiety to promote PTK6 ubiquitination and proteasomal degradation, inhibiting breast cancer cell proliferation, migration, and inducing apoptosis. MS105 is promising for research of breast cancer. Pink: BRK inhibitor P21d hydrochloride HY-115514 ; Black: linker HY-W105727 ; Blue: S,R,S -AHPC HY-125845 .
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