GENERAL CATALOGUE
MS181
HY-158239 · 5 mg
MedChemExpress · Cat: HY-158239
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Catalog No: HY-158239
Category: Metabolic Enzyme Protease
Pack Size: 5 mg
Brand: MedChemExpress
Description
MS181 compound 1 is a potent cereblon CRBN -recruiting and EED-binding polycomb repressive complex 1 PRC1 PROTAC degrader. MS181 decreases the expression of EED, EZH2, SUZ12, BMI1 and RING1B. MS181 shows antiproliferative activity Strtucture Note: Red, EED binder HY-158771 ; Blue, CRBN ligand HY-41547 ; Black, Linker HY-131717 .
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