

HY-125837A · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-125837A
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medchemexpress.com/ms31-trihydrochloride.html
Description
MS31 trihydrochloride is a potent, highly affinity and selective fragment-like methyllysine reader protein spindlin 1 SPIN1 inhibitor. MS31 trihydrochloride potently inhibits the interactions between SPIN1 and H3K4me3 IC50=77 nM, AlphaLISA; 243 nM, FP . MS31 trihydrochloride selectively binds Tudor domain II of SPIN1 Kd=91 nM . MS31 trihydrochloride potently inhibits binding of trimethyllysine-containing peptides to SPIN1, and is not toxic to nontumorigenic cells.







