GENERAL CATALOGUE
MS37452
HY-119344 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-119344
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Catalog No: HY-119344
CAS No: 423748-02-1
Category: Epigenetics
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
MS37452 is a potent inhibitor of CBX7 chromodomain binding to H3K27me3, with a Kd of 27.7 ?M. MS37452 can derepress transcription of polycomb repressive complex target gene p16/CDKN2A by displacing CBX7 binding to the INK4A/ARF locus in prostate cancer cells.
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