GENERAL CATALOGUE
MTX115325
HY-160019 · 1 mg
MedChemExpress · Cat: HY-160019
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medchemexpress.com/mtx115325.htmlCatalog No: HY-160019
CAS No: 2750895-97-5
Category: Autophagy
Pack Size: 1 mg
Brand: MedChemExpress
Description
MTX115325 Example 1 is an orally active, brain-penetrating USP30 inhibitor IC50=12 nM with neuroprotective activity. MTX115325 increases ubiquitination EC50=32 nM of the mitochondrial outer membrane protein TOM20 a USP30 substrate , increasing mitophagy. MTX115325 prevents dopaminergic neuron loss and preserves striatal dopamine.
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