GENERAL CATALOGUE
MU1210
HY-125290 · 5 mg
MedChemExpress · Cat: HY-125290
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medchemexpress.com/mu1210.htmlCatalog No: HY-125290
CAS No: 2275601-87-9
Category: Cell Cycle DNA Damage
Pack Size: 5 mg
Brand: MedChemExpress
Description
MU1210 compound 12f , a chemical probe, is an inhibitor of CDC-like kinases Clk1, Clk2, and Clk4 with IC50 values of 8, 20, and 12 nM respectively , with IC50 for HIPK1 and DYRK2 are 187 and 1309 nM. MU1210 also has favorable pharmacokinetic characteristics in mice, 10 mg/kg, intraperitoneal injection: Cmax=1.24 ?M, T1/2=58 minutes; no acute toxicity observed .