

HY-156470 · 50 mg
MedChemExpress · Cat: HY-156470
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medchemexpress.com/multi-kinase-in-6.html
Description
Multi-kinase-IN-6 compound 10e is a multikinase inhibitor that shows good enzyme inhibitory activity against TrkA, ALK2, c-KIT, EGFR, PIM1, CK2?, CHK1, and CDK2. Multi-kinase-IN-6 reveals antiproliferative activity against MCF7, HCT116 and EKVX with IC50 values of 3.36 ?M, 1.40 ?M and 3.49 ?M, respectively. Multi-kinase-IN-6 shows cell cycle arrest at the G1/S phase and G1 phase in MCF7 and HCT116 cells with good apoptotic effect.