

HY-158301 · 5 mg
MedChemExpress · Cat: HY-158301
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Manufacturer product page
medchemexpress.com/my-1b.html
Description
MY-1B is a covalent inhibitor of the RNA Methyltransferase NSUN2 IC50: 1.3 ?M . MY-1B stereoselectively ligands active-site cysteine residues C271 of NSUN2. MY-1B can stereoselectively and covalently bind to PSME1, disrupting the proteasome regulatory complex and downregulating the presentation of specific MHC-I subtypes.

