(")-Mycousnine

Description

AAasAasAa -Mycousnine is a microbial metabolite and derivative of Usnic Acid HY-N0656 originally isolated from M. nawae that has antibacterial and antifungal activities. It is active against the Gram-positive bacteria B. subtilis, K. rhizophila, and S. aureus MICs=4, 8, and 4 g/ml, respectively but not the Gram-negative bacteria E. coli, S. typhimurium, and K. pneumoniae MICs= 128 g/ml for all.2 AAasAasAa -Mycousnine is also active against the fungi T. mentagrophytes, T. rubrum, and C. albicans MICs=25, 25, and 100 ?g/mL, respectively .