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Myrothecine A
GENERAL CATALOGUE

Myrothecine A

HY-N8508 · 50 mg

MedChemExpress · Cat: HY-N8508

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medchemexpress.com/myrothecine-a.html
Catalog No: HY-N8508
CAS No: 910292-40-9
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress

Description

Myrothecine A is a trichothecene mycotoxin found in M. roridum. Myrothecine A induces apoptosis, promotes the cytochrome c release, PARP-cleavage and phosphorylation of JNK, increases Bax and cleaved caspase-3, -5, and -8 levels. Myrothecine A has anticancer activities and promotes the maturation of DC cells in the microenvironment. Myrothecine A inhibits proliferation of A549, MCF-7, HepG2, and SMMC-7721 cancer cells with IC50s of 95, 70, 60, and 25 AAasAasAAmuM, respectively.

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