GENERAL CATALOGUE
N-Desmethyl-Apalutamide
HY-135331 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-135331
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medchemexpress.com/n-desmethyl-apalutamide.htmlCatalog No: HY-135331
CAS No: 1332391-11-3
Category: Metabolic Enzyme Protease
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
N-Desmethyl Apalutamide is an active metabolite of Apalutamide. N-Desmethyl Apalutamide is a less potent antagonist of the androgen receptor and is responsible for one-third of the activity of Apalutamide. The formation of N-Desmethyl Apalutamide mediated predominantly by CYP2C8 and CYP3A4. N-Desmethyl Apalutamide is moderate to strong CYP3A4 and CYP2B6 inducer and has an excellent plasma-proteins bound concentration.
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