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N-Desmethylclozapine
GENERAL CATALOGUE

N-Desmethylclozapine

HY-G0021 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-G0021

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Catalog No: HY-G0021
CAS No: 6104-71-8
Category: Anti-infection
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

N-Desmethylclozapine is a major active metabolite of the atypical antipsychotic agent Clozapine. N-Desmethylclozapine is a potent, allosteric and partial M1 receptors agonist EC50=115 nM and is able to potentiate hippocampal N-methyl-d-aspartate NMDA receptor currents through M1 receptor activation. N-Desmethylclozapine is also a ?-opioid agonist.

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