GENERAL CATALOGUE
N-Desmethyltamoxifen hydrochloride
HY-129099A · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-129099A
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medchemexpress.com/n-desmethyltamoxifen-hydrochloride.html
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Catalog No: HY-129099A
CAS No: 15917-65-4
Category: Epigenetics
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
N-Desmethyltamoxifen hydrochloride is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potent protein kinase C PKC inhibitor than Tamoxifen. N-Desmethyltamoxifen hydrochloride is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation.
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