

HY-177337 · 50 mg
MedChemExpress · Cat: HY-177337
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medchemexpress.com/n-didesmethyladitoprim.htmlDescription
N-Didesmethyladitoprim is a metabolite of Aditoprime HY-139743 . Aditoprime is a selective bacterial dihydrofolate reductase DHFR inhibitor with IC50s of 47 and 520 nM for E.coli and L.casei DHFR , respectively. Aditoprime inhibits the transformation of dihydrofolic acid to tetrahydrofolic acid. Aditoprime has a broad-spectrum antibacterial activity and excellent pharmacokinetics.







