N-Hydroxysuccinimide

Description

N-Hydroxysuccinimide HOSu; 1-Hydroxy-2,5-pyrrolidinedione is a covalent crosslinker commonly used in bioconjugation technology with a primary amine group. N-Hydroxysuccinimide reacts with amino groups -NH2 to form a stable amide bond, which can modify amino-containing biomolecules. N-Hydroxysuccinimide can be used, for example, for protein labeling with fluorescent dyes and enzymes, surface activation of chromatography supports, microbeads, nanoparticles and microarray slides, and chemical synthesis of peptides. N-Hydroxysuccinimide has a wide range of applications in biomaterial synthesis such as collagen, chitosan crosslinking , drug delivery systems such as hydrogel preparation and tissue engineering.