GENERAL CATALOGUE
NA-Ir
HY-162944 · 50 mg
MedChemExpress · Cat: HY-162944
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medchemexpress.com/na-ir.htmlCatalog No: HY-162944
CAS No: 3031762-97-4
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
NA-Ir is a Ferroptosis inducer. NA-Ir targets mitochondrial DNA mtDNA and activates the cGAS-STING pathway to induce ferritinophagy Autophagy , while also generating reactive oxygen species ROS through photodynamic therapy PDT , depleting glutathione GSH , and downregulating glutathione peroxidase 4 GPX4 , thereby triggering lipid peroxidation and Ferroptosis. NA-Ir exhibits higher anticancer activity under light exposure and selectively inhibits cancer cells with high H2S levels.
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