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NADPH oxidase-IN-1
GENERAL CATALOGUE

NADPH oxidase-IN-1

HY-152026 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-152026

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Catalog No: HY-152026
CAS No: 2762405-17-2
Category: Metabolic Enzyme Protease
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

NADPH oxidase-IN-1 is an orally active NADPH oxidase Nox inhibitor, related with neuronal inflammation. NADPH oxidase-IN-1 can cross the blood-brain barrier BBB , inhibits Nox2 and Nox4 with IC50s of 1.9 ?M and 2.47 ?M, respectively. NADPH oxidase-IN-1 suppresses pro-inflammatory cytokines production and LPS-mediated microglial migration, also has in vivo efficacy.

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