

HY-152026 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-152026
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medchemexpress.com/nadph-oxidase-in-1.htmlDescription
NADPH oxidase-IN-1 is an orally active NADPH oxidase Nox inhibitor, related with neuronal inflammation. NADPH oxidase-IN-1 can cross the blood-brain barrier BBB , inhibits Nox2 and Nox4 with IC50s of 1.9 ?M and 2.47 ?M, respectively. NADPH oxidase-IN-1 suppresses pro-inflammatory cytokines production and LPS-mediated microglial migration, also has in vivo efficacy.







