GENERAL CATALOGUE
Naldemedine
HY-19627 · 50 mg
MedChemExpress · Cat: HY-19627
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Catalog No: HY-19627
CAS No: 916072-89-4
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
Naldemedine S-297995 is an orally active ?-opioid receptor antagonist PAMORA . Naldemedine shows potent binding affinities Ki=0.34, 0.43, 0.94 nM, respectively and antagonist activities IC50=25.57, 7.09, 16.1 nM, respectively for recombinant human ?-, ?-, and ?- opioid receptors. Naldemedine can be used in opioid-induced constipation OIC research. Naldemedine is predicted to bind to 3CLpro encoded by SARS-CoV2 genome.
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