GENERAL CATALOGUE
NAMPT inhibitor-linker 2
HY-112616 · 5 mg
MedChemExpress · Cat: HY-112616
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medchemexpress.com/NAMPT_inhibitor-linker_2.htmlCatalog No: HY-112616
CAS No: 2241014-82-2
Category: Antibody-drug Conjugate ADC Related
Pack Size: 5 mg
Brand: MedChemExpress
Description
NAMPT inhibitor-linker 2 is a agent-linker conjugates for ADC, composed of an NAMPT inhibitor as a payload, and a linker. ADC-4 consists of an NAMPT inhibitor-linker 2 and an anti-c-Kit monoclonal antibody, exihibits potent activity against c-Kit expressing cell lines such as GIST-T1 and NCI-H526, with IC50s of <7 pM and 40 pM, respectively.
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