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Naph-Se-TMZ
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Naph-Se-TMZ

HY-169433 · 50 mg

MedChemExpress · Cat: HY-169433

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medchemexpress.com/naph-se-tmz.html
Catalog No: HY-169433
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress

Description

Naph-Se-TMZ is a PROTAC-like HDAC1 degrader. Naph-Se-TMZ can reduce the total HDAC activity in glioma cells and enhance the inhibitory effect of Temozolomide HY-17364 . Naph-Se-TMZ consists of the target protein ligand red part Temozolomide HY-17364 , the DNA-targeting intercalator blue part Nitro-Naphthalimide-C2-acylamide HY-169437 and the molecular linker black part . At the same time, the active control of the target protein ligand is: Temozolomide-amino hydrochloride HY-169439 , and the DNA targeting intercalator + linker is: NNISC-2 HY-169438 .

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