Naphthol AS-MX phosphate

Description

Naphthol AS-MX phosphate NASTRp is a small molecule inhibitor of the CREB cyclic adenosine phosphate reaction element binding protein -CBP CREB binding protein transcription factor complex. Naphthol AS-MX phosphate shows antitumor activity against lung cancer cells, inhibiting tumor cell proliferation IC50=3.701 ?mol/L , colony formation, and anchored independent growth in soft AGAR. Naphthol AS-MX phosphate can be used in the study of KRAS mutated lung cancer, especially for KRAS mutated lung cancer with poor chemotherapy resistance and prognosis.