GENERAL CATALOGUE
Naratriptan
HY-B0197 · 1 mg
MedChemExpress · Cat: HY-B0197
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Catalog No: HY-B0197
CAS No: 121679-13-8
Category: GPCR G Protein
Pack Size: 1 mg
Brand: MedChemExpress
Description
Naratriptan is an orally active and selective 5-HT1B/1D receptor agonist. Naratriptan is peripherally active and has good oral bioavailability, inducing cranial artery vasoconstriction by activating 5-HT1B/1D receptors EC50=0.11 ?M for dog basilar artery . Naratriptan also inhibits trigeminal nerve-mediated dural neurogenic plasma extravasation and reduces sterile inflammation. Naratriptan is mainly used in the research of acute migraine, targeting cranial vascular and neuroinflammatory mechanisms.
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