Naratriptan hydrochloride (Standard)

Description

Naratriptan GR-85548A hydrochloride Standard is the analytical standard of Naratriptan hydrochloride HY-B0197A . This product is intended for research and analytical applications. Naratriptan is a selective 5-HT1B/1D receptor agonist. Naratriptan is peripherally active and has good oral bioavailability, inducing cranial artery vasoconstriction by activating 5-HT1B/1D receptors EC50=0.11 ?M for dog basilar artery . Naratriptan also inhibits trigeminal nerve-mediated dural neurogenic plasma extravasation and reduces sterile inflammation. Naratriptan is mainly used in the research of acute migraine, targeting cranial vascular and neuroinflammatory mechanisms.