GENERAL CATALOGUE
Navacaprant
HY-124754 · 5 mg
MedChemExpress · Cat: HY-124754
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medchemexpress.com/navacaprant.htmlCatalog No: HY-124754
CAS No: 2244614-14-8
Category: GPCR G Protein
Pack Size: 5 mg
Brand: MedChemExpress
Description
Navacaprant BTRX-335140 is a selective and orally active ? opioid receptor KOR antagonist, has antagonist activity for ?OR, ?OR and ?OR with IC50 values of 0.8 nM, 110 nM, and 6500 nM, respectively. Navacaprant endows with favorable in vitro ADMET and in vivo pharmacokinetic profiles and medication-like duration of action in rats. Navacaprant distributes well into the CNS and can be used for the research of neuropathy.
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