GENERAL CATALOGUE
NBI-42902
HY-13699 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-13699
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Catalog No: HY-13699
CAS No: 352290-60-9
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
NBI-42902 is an orally active, potent functional and competitive antagonist of GnRH receptor with an IC50 value of 0.79 nM, a Ki value of 0.56 nM, respectively. NBI-42902 inhibits GnRH-stimulated inositol phosphate IP accumulation, Ca2+ flux, and ERK1/2 activation. NBI-42902 inhibits serum luteinizing hormone LH in castrated male macaques. NBI-42902 can be used for research on sex-hormone-related diseases.
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