GENERAL CATALOGUE
NC-III-49-1
HY-150683 · 50 mg
MedChemExpress · Cat: HY-150683
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medchemexpress.com/nc-iii-49-1.htmlCatalog No: HY-150683
CAS No: 3031654-46-0
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress
Description
NC-III-49-1 is a potent bivalent bromodomain and extraterminal domain BET inhibitor. NC-III-49-1 shows binding potential for BRD4-1, BRD4-2, BRD4-T, BRDT-1, BRDT-2, BRDT-T with Kd values of 0.095, 0.32, 0.29, 0.089, 5.5, 0.058 nM, respectively. NC-III-49-1 shows antiproliferative activity. NC-III-49-1 decreases the expression of c-Myc.