GENERAL CATALOGUE
NC-R17
HY-155075 · 50 mg
MedChemExpress · Cat: HY-155075
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medchemexpress.com/nc-r17.htmlCatalog No: HY-155075
CAS No: 3049087-34-2
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
NC-R17 is a PROTAC-class, non-covalent GPX4 degrader based on RSL3, involved in ferroptosis. NC-R17 has antitumor activity and is used for non-covalent GPX4 PROTAC design. NC-R17 consists of a target protein ligand red part Demethyl-RSL3 HY-135832 ; an E3 ubiquitin ligase ligand blue part Lenalidomide HY-A0003 and a PROTAC linker black part HY-169376 . E3 ubiquitin ligase and linker can form Lenalidomide-C13-piperazine-Boc HY-169377 .
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