

HY-P991223 · 1 mg
MedChemExpress · Cat: HY-P991223
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medchemexpress.com/nc762.htmlDescription
NC762 is a humanized IgG1? monoclonal antibody that targets human B7-H4 B7 homolog 4 . NC762 has enhanced binding to CD16a Fc?RIIIa after being Fc engineered with three point mutations S239D/A330L/I332E; DLE and demonstrate increased antibody-dependent cellular cytotoxicity ADCC activity. NC762 inhibits tumor growth in vivo through binding to tumor-expressing B7-H4. NC762 can be studies in research on cancer such as advanced or metastatic solid tumors.







