GENERAL CATALOGUE
NCAO
HY-160843 · 5 mg
MedChemExpress · Cat: HY-160843
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Catalog No: HY-160843
CAS No: 20584-81-0
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress
Description
N-?-chloroacetyl-L-ornithine NCAO is a potent reversible competitive ornithine decarboxylase ODC inhibitor that exerts cytotoxic and antiproliferative effects on tumor cell lines with EC50 values ranging from 1 to 50.6 AAasAasAAmuM. NCAO induces tumor cell Apoptosis and inhibits tumor cell migration in vitro. NCAO also exhibits a potent antitumor activity against both solid and ascitic tumors in a mouse model using the myeloma Ag8 cell line. NCAO is promising for research of antitumor agents.
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