

HY-120766 · 5 mg
MedChemExpress · Cat: HY-120766
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Manufacturer product page
medchemexpress.com/ncdm-32b.html
Description
NCDM-32B is a potent and selective KDM4 inhibitor, with IC50 values of 3.0 ?M for KDM4A and 1.0 ?M for KDM4C in in vitro enzyme assays. NCDM-32B specifically increases global H3K9me3/me2 levels in basal breast cancer cells. NCDM-32B impairs the viability of KDM4C-amplified basal breast cancer cell lines HCC1954 and Colo824 . NCDM-32B can be used for the study of breast cancer.

