NCE2 Rabbit Monoclonal Antibody

Description

EnkiLife offers the NCE2 Rabbit Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB,IHC,ICC/IF application. Alternative Names of Immunogen: NCE2; NEDD8 carrier protein UBE2F; NEDD8 protein ligase UBE2F; NEDD8-conjugating enzyme 2. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200 Background: Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5. Research Area: Epigenetics and Nuclear Signaling