GENERAL CATALOGUE
NCGC00378430
HY-138657 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-138657
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Catalog No: HY-138657
CAS No: 920650-00-6
Category: Metabolic Enzyme Protease
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
NCGC00378430 is a potent SIX1/EYA2 interaction inhibitor. NCGC00378430 partially reverses transcriptional and metabolic profiles mediated by SIX1 overexpression and reverses SIX1-induced TGF-? signaling and epithelial-mesenchymal transition EMT . NCGC00378430 inhibits SIX1-mediated breast cancer metastasis in a mouse model.
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