GENERAL CATALOGUE
NCI677397
HY-176557 · 50 mg
MedChemExpress · Cat: HY-176557
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Manufacturer product page
medchemexpress.com/nci677397.htmlCatalog No: HY-176557
CAS No: 907547-06-2
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
NCI677397 is a USP24 inhibitor. NCI677397 increases lipid ROS, activates cholesterol and fatty acid biosynthesis, degrades ABC transporters, GPX4 and DHFR through the autophagy pathway, decreases the level of P-gp and ultimately leads to ferroptosis in drug-resistant cancer cells. NCI677397 can be used for the study of lung caner and brain cancer.
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