NCS-MP-NODA

Description

NCS-MP-NODA NODA-Bz-SCN is a bifunctional chelator that can be used to bind to the labeled peptide DK222 with high specificity for PD-L1. The corresponding fluorinated radioactive is synthesized by the aluminum fluoride method, and NCS-MP-NODA targets DK222 to obtain the radioactive analog 18/19F DK222. 18F DK222 can quantify PD-L1 in vivo via PET tracking in xenograft models of multiple cancer types.