GENERAL CATALOGUE
ND-2110
HY-117622 · 50 mg
MedChemExpress · Cat: HY-117622
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medchemexpress.com/nd-2110.html
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Catalog No: HY-117622
CAS No: 1388894-17-4
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress
Description
ND-2110 is a selective IRAK4 inhibitor Ki: 7.5 nM . ND-2110 binds to the ATP pocket of IRAK4. ND-2110 targets the subset of activated B cell-like ABC subtype of diffuse large B cell lymphoma DLBCL cell lines with MYD88 L265P mutations,. ND-2110 inhibits LPS-induced TNF production, alleviates collagen-induced arthritis, and blocks gout formation in mouse models.
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