

HY-149432 · 50 mg
MedChemExpress · Cat: HY-149432
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medchemexpress.com/ndna3.html
Description
NDNA3 compound 14 is a selective inhibitor of Hsp90? IC50: 0.51 ?M . NDNA3 is a permanently charged analog with low membrane permeability and low toxicity to Ovcar-8 IC50: 12.66 ?M and MCF-10A IC50: 11.72 ?M cells. NDNA3 prevents disruption of hERG channel maturation without generating a heat shock response or causing degradation of Hsp90?-dependent client proteins.





