

HY-149431 · 50 mg
MedChemExpress · Cat: HY-149431
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medchemexpress.com/ndna4.htmlDescription
NDNA4 compound 17 is a selective inhibitor of Hsp90? IC50: 0.34 ?M . NDNA4 is a permanently charged analog with low membrane permeability and low cytotoxicity against Ovcar-8 and MCF-10A IC50 100 ?M . NDNA4 prevents disruption of hERG channel maturation without generating a heat shock response or causing degradation of Hsp90?-dependent client proteins.





