GENERAL CATALOGUE
Nebentan
HY-106994 · 50 mg
MedChemExpress · Cat: HY-106994
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medchemexpress.com/nebentan-free-base.htmlCatalog No: HY-106994
CAS No: 403604-85-3
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
Nebentan YM598 free base is a potent, selective and orally active non-peptide endothelin ETA receptor antagonist through the modification of Bosentan HY-A0013 . Nebentan inhibits 125I endothelin-1 binding to cloned human endothelin ETA and ETB receptor, with Ki of 0.697 nM and 569 nM, respectively. YM598 can ameliorate the progression of cor pulmonale and myocardial infarction in vivo.
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