

HY-106994A · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-106994A
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Manufacturer product page
medchemexpress.com/nebentan-potassium.html
Description
Nebentan potassium YM598 is a potent, selective and orally active non-peptide endothelin ETA receptor antagonist through the modification of Bosentan HY-A0013 . Nebentan potassium inhibits 125I endothelin-1 binding to cloned human endothelin ETA and ETB receptor, with Ki of 0.697 nM and 569 nM, respectively. YM598 can ameliorate the progression of cor pulmonale and myocardial infarction in vivo.







