GENERAL CATALOGUE
NecroX-7
HY-124750 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-124750
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Catalog No: HY-124750
CAS No: 1120332-55-9
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
NecroX-7 is a potent free radical scavenger and a HMGB1 high-mobility group box 1 inhibitor. NecroX-7 can be used as an antidote to acetaminophen toxicity. NecroX-7 exerts a protective effect by preventing the release of HMGB1 in ischemia/reperfusion injury. NecroX-7 inhibits the HMGB1-induced release of TNF and IL-6, as well as the expression of TLR-4 and receptor for advanced glycation end products. NecroX-7 can be used graft-versus-host disease GVHD research.
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